Ana M Cosialls Selected Research

Prohibitins

12/2023	The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
9/2021	The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
1/2021	NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
10/2020	The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
1/2017	The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.
10/2016	Targeting prohibitins induces apoptosis in acute myeloid leukemia cells.

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Ana M Cosialls Research Topics

Disease

8	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2017 - 12/2006
7	Neoplasms (Cancer) 12/2023 - 12/2006
2	Hematologic Neoplasms (Hematological Malignancy) 12/2023 - 09/2021
2	Leukemia 01/2021 - 02/2010
2	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2010 - 05/2006
1	Lung Neoplasms (Lung Cancer) 09/2021
1	Multiple Myeloma 10/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2016
1	Neuroblastoma 07/2011
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 12/2006
1	Lymphoma (Lymphomas) 12/2006

Drug/Important Bio-Agent (IBA)

6	ProhibitinsIBA 12/2023 - 10/2016
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 12/2006
2	acadesineIBA 01/2017 - 10/2010
2	AICA ribonucleotide (ZMP)IBA 08/2013 - 10/2010
1	Carbonyl Cyanide m-Chlorophenyl Hydrazone (CCCP)IBA 09/2021
1	rocaglamideIBA 09/2021
1	ibrutinibIBA 01/2017
1	venetoclaxIBA 01/2017
1	GlucocorticoidsIBA 09/2012
1	kendine 92IBA 10/2011
1	Histone Deacetylase InhibitorsIBA 10/2011
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 07/2011
1	Messenger RNA (mRNA)IBA 07/2011
1	RoscovitineIBA 07/2011
1	NF-kappa B (NF-kB)IBA 02/2010
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2010
1	A 443654IBA 12/2009
1	Chemokine CXCL12IBA 12/2009
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 12/2009
1	Interleukin-4 (Interleukin 4)IBA 12/2009
1	Antineoplastic Agents (Antineoplastics)IBA 12/2007
1	PK 11195 (PK11195)IBA 12/2007
1	Phosphatidylinositols (Phosphatidylinositol)IBA 12/2006
1	Antimycin AIBA 12/2006
1	Protein Kinase C betaIBA 12/2006
1	nutlin 3IBA 05/2006

Therapy/Procedure

1	Ligation 10/2012
1	Therapeutics 07/2011
1	Drug Therapy (Chemotherapy) 12/2006